Home Black Seeds Update: Nigalla sativa Reverses Hypothyroidism

Update: Nigalla sativa Reverses Hypothyroidism

by Sean Martu

I wrote an article a couple of years ago elucidating research proclaiming that Powdered Black Seeds(Nigella Sativa) reversed Hashimoto’s hypothyroid. But I’ve recently discovered more verifying research as well as a testimony from one of my youtube followers.

I’m not going to go over all the details of what exactly is hypothyroidism, its symptoms, and its known causes, if you need that residual knowledge, read my article, “How to naturally cure your hypothyroidism including Hashimoto’s“.

Although, I will still mention that hypothyroidism is at epidemic levels among American women.

So what did I find?

In the PubMed article, “Powdered black cumin seeds strongly improves serum lipids, atherogenic index of plasma and modulates anthropometric features in patients with Hashimoto’s thyroiditis” –


Forty patients with Hashimoto’s thyroiditis, aged between 22 and 50 years old, participated in the trial and were randomly allocated into two groups of intervention and control receiving powdered Nigella sativa or placebo daily for 8 weeks. Serum lipids, glucose homeostasis, and anthropometric variables were evaluated at baseline and after intervention.


Treatment with Nigella sativa significantly reduced body weight and body mass index (BMI). Serum concentrations of low density lipoprotein cholesterol (LDL) and triglyceride (TG) also decreased in Nigella sativa-treated group after 8 weeks; while serum high density lipoprotein cholesterol (HDL) significantly increased after treatment with Nigella sativa (P < 0.05). None of these changes had been observed in placebo treated group. Serum Nesfatin-1 concentrations was in inverse relationship with serum triglyceride (TG) (r = − 0.31, P = 0.04).


Methods: Thirty pregnant rats were kept in separate cages. After delivery, the mothers and their offspring were randomly divided into six groups including: (1) control, (2) PTU (propylthiouracil), (3) PTU-NS 100, (4) PTU-NS 200, (5) PTU-NS 400, and (6) PTU-Vit C (vitamin C). All dams except the control group received 0.005% PTU in their drinking water during lactation. Besides PTU, dams in groups 3, 4, 5, and 6 received 100, 200, and 400 mg/kg N. sativa extract, or 100 mg/kg Vit C, respectively. After lactation period, pups continued to receive same experimental treatment for the first 8 weeks of their life. Then, 10 male offspring of each group were randomly selected and assessed for the learning and memory abilities by using Morris water maze (MWM) and passive avoidance (PA) tests. Blood samples were collected for thyroxine assessment, animals were euthanized, and the brain tissues were removed and analyzed for total thiol groups and malondialdehyde (MDA) concentrations.


Results: PTU exposure significantly increased the time latency in MWM test, while reduced the time spent in target quadrant, and decreased the latency for entering the dark compartment in PA test. These effects were associated with significant reduction in serum thyroxine levels and brain levels of thiol groups, and significant elevation in hippocampal MDA. Administration of 400 mg/kg N. sativa extract and 100 mg/kg Vit C reduced the time latency, while increased the time spent in target quadrant compared to the PTU group in MWM test. Treatment by 100-400 mg/kg of N. sativa extract and also Vit C significantly increased the time latency for entering the dark compartment in PA test. The serum thyroxine concentrations of the animals treated by all doses of the N. sativa extract as well as by Vit C were higher than that of the PTU group. Two hundred and four hundred milligrams/kilogram of NS extract and 100 mg/kg Vit C decreased the MDA concentration in hippocampal tissues, while increased thiol contents compared to the PTU group.


Discussion: The results of this study demonstrate that the hydroalcoholic extract of N. sativa have protective effects on hypothyroidism-associated learning and memory impairment during neonatal and juvenile growth in rats. The effects were comparable to Vit C and might be due to the protective effects of N. sativa extract against brain tissues’ oxidative damage.

In the third PudMed article, ” Neuroprotective effects of Nigella sativa extract upon the hippocampus in PTU-induced hypothyroidism juvenile rats: A stereological study” –

This study aimed to examine the neuroprotective effects of Nigella sativa (N. sativa) in the hippocampus of propylthiouracil (PTU)-induced hypothyroid rats during neonatal and juvenile growth. Twenty- five pregnant rats from early gestation (GD 0) were divided into five groups: (1) control (received drinking water), (2) PTU (received 0.005% PTU in drinking water), (3-5) PTU + NS 0.05%, PTU + NS 0.1%, PTU + NS 0.2% (along with PTU, received 0.05%, 0.1% and 0.2% W/V of N. sativa respectively) and treatment continued until postnatal day 60 (PN 60). The brains of male pups were removed for histological and stereological assessments. N. sativa extract significantly reduced the production of dark neurons and apoptotic cells in different areas of the hippocampus compared to the PTU group. Moreover, it significantly attenuated the effect of hypothyroidism on the volume reduction of the hippocampus. The results of the present study suggested that N. sativa extract has a potential ability to prevent the hippocampal neural damage after inducing hypothyroidism during neonatal and juvenile growth in rats.

All three research articles elucidate the protective and healing results of ingesting powdered black seeds or their extracts.

But what one of my youtube followers posted below even had me mystified.

She reported that she had only taken powdered black seeds for two weeks, and she did a test and her thyroid came back functioning in a normal range. Every time I read this it blows me away.

You can purchase Powdered black seeds from my websites in 90 vegan pills, 2 oz bag, 6 oz bag, 12 oz bag, and a 1 lb bag.

Necessary internet disclaimer:  All information and resources found on Nothingsincurable.com are based on the opinions of the author unless otherwise noted. I am not a doctor nor do I have any medical training, all information is intended to motivate readers to make their own nutrition and health decisions after consulting with their health care provider. The author of this site encourages you to consult a doctor before making any health changes, especially any changes related to a specific diagnosis or condition.


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Denise Zientek May 4, 2022 - 1:53 am

I have stage four colon cancer that has metastized to the ovaries liver and lungs. My question is about dosages how much and how often would I take the black seed powder or should I use the oil or both? The organic lemons how often? The complex vitamin C? I just need to know dosages and times to take it and I would be willing to try it otherwise I’m lost. Thank you and God bless. Denise
how does one get the wild oil of oregano from another country? Is there a website?

Sean Martu
Sean Martu May 4, 2022 - 1:54 am

Take a tablespoon of black seed oil in the morning and when you go to bed. Take a tsp a powdered black seeds in the morning and at night and mix it with a teaspoon of raw unfiltered honey

Sean Martu
Sean Martu May 4, 2022 - 1:55 am

If you want to add the lemon juice juice one organic lemon the day the whole lemon in a smoothie and drink it

Sean Martu
Sean Martu May 4, 2022 - 1:56 am

You can get camu camu, or a ascerola cherry or a kakadu plum in a powdered form make sure it has at least 650% of vitamin C per teaspoon for it to work I think about 4 tsp a day 2 in the morning to at night

Sean Martu
Sean Martu May 6, 2022 - 4:22 am

Take both powder and the oil, take a teaspoon of the powder and a tablespoon of the oil twice a day

Sean Martu
Sean Martu May 6, 2022 - 4:23 am

You can get both on my site, I ship worldwide

Michelle Dill May 4, 2022 - 10:41 pm

I make a honey bomb with turmeric, ginger, cinnamon and pepper and take a teaspoon daily. Can I add the black seed to it as well?

Sean Martu
Sean Martu May 4, 2022 - 10:56 pm


Tami Pafford May 6, 2022 - 5:38 pm

What is the difference between fresh water DE and ocean water DE and which one should I use?


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